Abstract: Cooling load participating in operation regulation can effectively reduce the micro-grid energy supply burden and renewable energy fluctuation deviation. The optimal control model is established by taking air conditioner as an example,two-stage optimal operation model of micro-grid is proposed considering the cooling load flexible regulation. In the first stage,with the goal of minimizing operation cost,the collaborative optimization model of multi-energy equipment in micro-grid is established to optimize the operation strategy of cooling load,energy storage equipment,diesel generators and the power purchase scheme from power grid. In the second stage,with the goal of minimizing the fluctuation cost and residual fluctuation deviation of renewable energy,the fluctuation power stabilization model is established,including the response characteristics of various types of resources,such as cooling load and energy storage device. The micro-grid system composed of three commercial buildings and wind-photovoltaic-diesel-storage is used to verify the effectiveness of the proposed model. The simulation results show that the economy of micro-grid operation can be improved and the fluctuating power of new energy can be reduced without affecting the satisfaction of users through cool load optimal regulation. The overall operating cost of micro-grid can be reduced by 3.3%,and the fluctuating power of new energy can be reduced by about 61%.