As the driving force in enhancing industrial and supply chains resilience，the high-quality development of specialized，refined，distinctive and innovative enterprises is crucial for the national economic transformation. This study adopted a mixed-method approach integrating qualitative meta-analysis and dynamic QCA to systematically explore their high-quality development pathways，overcoming the limitations of single-method approaches. We proposed a three-dimensional "Resources-Strategy-Context" framework，identifying these dimensions as key determinants of high-quality development，though no single dimension constitutes a necessary condition. Configuration analysis revealed the following:（1） There are four high-quality development pathways—opportunity-driven，first-mover advantage，steady progression，and policy-enabled types，as well as two non-high-quality development pathways，resource-constrained and strategy-mismatched types； （2） Low R&D investment serves as core condition for high-quality development pathways，whereas high R&D investment correlates with non-high-quality development； （3） Social capital demonstrates a double-edged sword effect. It facilitates growth under policy environment but exacerbates underperformance in weak policy environment and innovation climate.