In order to solve the problems that the natural cracks of the dense sandstone reservoir in Sichuan region is undeveloped with low hole

low permeability and strong spatial heterogeneity

the transformation idea of “segment clusters created + sand + high strength long slot” is established by the indoor model experiments. On this basis

a calculation model of stress field around the wells based on the effective stress theory is established. Meanwhile

the above model is combined with the flow-stress coupling fracture extension model for horizontal wells to clarify the influence mechanism of cluster spacing on the crack competition expansion and interseam seepage interference. Therefore

the non-uniform arrangement method of cracks in the sand body of river channel considering stress interference and seepage shadow is formed. It is concluded that the optimal spacing of multiple clusters in the horizontal well section of dense sandstone in Qiulin is seven to twelve meters

which can make the opening rate of the injection cluster up to 92.3 %. This method effectively improves the effect of the transformation of the tight gas reservoirs.