Cement-soil retaining wall is widely used for excavation supporting in soft soil area. Aiming at the deficiency of view on correlation between stability of cement-soil retaining wall and its influential factors
orthogonal design method is introduced to analyze the significance and sensitivity of some influential factors such as wall width,embedded depth,shear strength indices,unit weights,groundwater levels and ground load. The analytical result shows that the shear strength indices are the most important and sensitive factors influencing the overall stability of cement-soil retaining wall; and the change of shear strength indices has highly prominent influence on the overall stability of cement-soil retaining wall. But the change of wall width and embedded depth has no prominent influence on the overall stability of cement-soil retaining wall. The conclusions may be useful for the design and construction of cement-soil retaining wall.