Pulsed magnetic field treatment with cancer has good application prospects depending on its advantages of non-invasive. One of the mechanisms for pulsed magnetic field causing biological effects is from the induced electric field and magnetic field induced current. In order to obtain a larger induced electric field to carry out the cell experiments of pulsed magnetic field treatment on tumor cells

we develop a pulsed magnetic field generator with a high-variation rate by Archimedes spiral coil and the self-breakdown air switch. And we calculate the magnetic field and the induced electric field around the Archimedes spiral coil. By using COMSOL Multiphysics software

magnetic field distribution characteristic of coil is optimizing designed. Then the performance of the generator is measured. Finally

the Archimedean spiral coil has 7 turns

and the outer diameter is 21 mm. The pulsed magnetic field parameters can be produced in the cell culture medium as follows: the magnetic induction magnitude of 0.92 T

the rise time of 78 ns

the pulse width of 1.8 μs. And rate of change of magnetic field reaches 1.1×107 T/s

induced electric field maximum is 55.9 kV/m

electric field uniform degree can achieve 84%

and the maximum of the induced current density reaches 1.7×104 A/m2. The results show that the pulsed magnetic field generator can meet the requirements of the experiment cells associated with pulsed magnetic therapy treating with tumors

which lay the foundation for future study.