Abstract: The linear section location method based on remote signaling data does not consider the influence of communication time-delay and reliability, and is only applicable to large current faults and single faults. In this regard, a multi-point synchronous protection scheme for active distribution network based on 5G communication is proposed. Firstly, a section location communication architecture based on 5G communication is established, and its communication time-delay and reliability are analyzed. Secondly, on the basis of analyzing the direction distribution characteristics of the transient zero-sequence current, the switching function is redefined, and a logical relationship location model suitable for small current faults is proposed. Then, using the left-right approximation method, the switching function established according to the logic relationship is linearized, which makes the linearized logic relationship location model not only suitable for single faults, but also for multiple faults. Finally, the proposed protection scheme is validated in an active distribution network with different topologies and 5G communication. The results show that the proposed scheme can not only realize multi-point synchronous protection, but also be applicable to both small current faults and multiple faults.