Abstract: The stochastic fluctuations of wind increase the difficulty in operating scheduling in power system.This paper established a generation scheduling model and operation simulation model considering demand response in large-capacity wind power integrated system.In the model reserve cost for wind power was incorporated into objective function and up spinning reserve and down spinning reserve were considered.Load curve was predicted according to user response principle based on consumer psychology and interrupted load acted as part of system reserve.The effectiveness of TOU and IL was integrated into one model on account of coordinating generate and demand side,which could respond to characteristic of negative peaking load shifting intermittency of wind power.The wind energy curtailment and loss of load before and after considering demand side response under varieties of wind power outputs were estimated by Monte Carlo simulation.The relationship between wind power penetration and wind energy curtailment and the one between wind power capacity and loss of load were presented in this paper.The simulation on IEEE 24-bus system indicated this model can decrease the generating cost effectively and increase utilization ratio and levels of capacity usage of wind power.