Abstract: In order to save energy, reduce emission and improve energy efficiency, this paper proposed a logistics-energy collaborative optimization scheduling method for large seaport integrated energy system, which fully tapped the economic optimization potential of the combination of logistics system and energy system. First, considering the relationship between the number of quay cranes allocated and the status of ships in the port, a logistics system dispatch model was established. Secondly, combining the ship's status in the port and the characteristics of shore-side power, from the load point of view, a coupled load model of the logistics-energy system of the ship and the quay crane was established. Finally, with the goal of the lowest operating cost, the logistics system and the energy system were coordinated to optimize the ship load operation strategy and the quay crane dispatching plan, as well as the output of various energy equipment. Taking a port in Shanghai as an example, the results show that the proposed method can effectively integrate the port logistics system and the energy system on the basis of fullly considering of ship itinerary arrangements, reduce operating costs and carbon emissions, and improve energy utilization.