Abstract: With the development of the park integrated energy system, there usually are multiple park integrated energy systems in the same power distribution area, which form the multi-microgrids integrated energy system or multi-microgrids system combined with cold, hot and electricity. An optimal dispatching strategy based on the integrated demand response and leader-followers game was proposed for the multi-microgrids integrated energy system with electric power interaction. Firstly, an integrated demand response model was established includes shiftable disturbed electrical load, shiftable undisturbed electrical load, flexible thermal load and cooling load. Then, a leader multi-followers interaction equilibrium model was formed with the setting where multi-microgrids system as the leader and the multi-microgrids users as the followers, which optimized the pricing strategy of the multi-microgrids system, the demand response scheme of each microgrid users and the output of various energy conversion coupling devices in the multi-microgrids system at the same time, besides, the existence and uniqueness of the equilibrium solution of the game were proved. Finally, the rationality and effectiveness of the proposed strategy were demonstrated through the case analysis. There is to say, the profitability of the multi- microgrids system and the comprehensive benefit and energy cost of each microgrid users are improved.