Abstract: The high proportion of wind power grid-connected brings challenges to power system dispatch and operation. To deal with the uncertainty of wind power, a two-stage robust unit commitment (UC) model considering operational risk and demand response was proposed in this paper. The model has the following characteristics: 1) Based on historical wind power prediction and measurement data, the distribution characteristics of wind power prediction errors were analyzed, and an operation risk model based on 0-1 programming was established; 2) Integrating the established operational risk model into the robust UC model, by solving the robust UC model and dynamically adjusting the boundary of the wind power admissibility area, the cooperative optimization of operational cost and operational risk was realized; 3) The influence of TOU price on load demand was considered, and the influence of demand response uncertainty on the dispatching result was analyzed. The proposed model was solved by Benders-C & CG method. The simulation results show that the proposed model can dynamically adjust the boundary of wind power uncertainty sets, and effectively reduce the total cost of operation cost and operation risk.