Abstract: With the rapid development of power internet of things（IoT）, the models for centralized control cyber power physical system（CPPS） is increasingly unable to meet the need of the large scale power grid with massive data. Based on the cloud-edge collaborative data processing, this paper modeled a new centralized-distributed joint control CPPS after constructing a power IoT architecture. Adopting cloud-edge collaborative centralized-distributed joint control mechanism, a layered autonomous collaborative network architecture（ACNA） was built on the basis of reasonable CPPS division taking edge computing group as a basic unit. A unit-level CPPS model was established with matrix tools and edge computing. The unified calculation model was developed combining the multi-shot ACNA model with the mathematical model of power network. Numerical examples illustrate the rationality and superiority of the unified calculation model.