Abstract: In order to adapt to the current and future large-scale renewable energy integration in grid, the conventional superheated steam temperature（SST） cascade PID control scheme of thermal power unit is difficult to achieve higher control quality under the requirement of depth peak load cycling. To this end, this paper introduced cascade active disturbance rejection predictive control strategy combining dynamic matrix control（DMC） and active disturbance rejection control（ADRC）, to improve the SST control performance. Specifically, in order to overcome uncertain disturbance factors such as control variables and compensate time delay, discrete predictive ADRC control was adopted in the inner-loop, which is more suitable for fast process and can estimate and compensate disturbance in real time. And the predictor part of the aforementioned control was to predict the inner-loop output to compensate the influence of time delay. Besides, DMC adapted to slow process was also employed in the outer-loop for enhancing the set-point tracking ability and robustness. Taking the ultra-supercritical superheated temperature system as an example, simulation results show that the proposed control strategy has better performance of set-point tracking, disturbance rejection and robustness than other cascade control methods.