Abstract: To achieve the harmless, reduced, and resourceful treatment of medical waste while enhancing energy and material utilization efficiency, a hydrogen/methanol production system based on plasma medical waste gasification technology is proposed to produce hydrogen/methanol. Among them, the hydrogen production system（scheme A） converts medical waste into hydrogen;The dual fuel system of hydrogen and methanol production（scheme B） converts medical waste into hydrogen and methanol. All schemes use a 30 t/d plasma gasifier and are evaluated and compared from a thermodynamic and economic point of view. The results show that the process efficiencies of scheme A and scheme B reach 70.07% and 67.96%, respectively. Due to the recycling of waste gas, the system breakdown efficiency of scheme B is 2.19 percentage points higher than that of scheme A. Compared with scheme B, scheme A has a shorter dynamic payback period of 4.40 years and a relatively higher net present value of 255.57 million yuan.