Abstract: High-precision fluid-structure interaction simulation is an effective method for studying the structural reliability of wind turbines under typhoon conditions. However, the substantial computational costs and issues related to negative volume grids significantly affect the efficiency and stability of simulation. In this study, an improved fluid-structure interaction method was applied to investigate the load and response characteristics of wind turbines at different wind spe eds. Its accuracy was validated using NREL data and wind turbine blade modal vibration experiments. Compared to traditional fluid-structure coupling methods, this approach reduces the number of dynamic grids used, avoids negative volume grids, enhances computational stability, and shortens computation time by approximately 50%. Simulation results indicate that increasing the wind speed from 25 m/s to 35 m/s leads to a 6.8-fold increase in fluctuation amplitude for blade thrust and a 9.8-fold increase for torque loads. Additionally, structural buckling was observed on the suction side of the blade, which is close to the location of blade fractures observed in actual typhoon conditions. This may indicate a structural weak point of wind turbine blades under typhoon environments, offering valuable insights for subsequent wind turbine design optimization.