Abstract: The interaction of wake effects and complex topography in mountainous wind farms poses challenges to power generation and escalates the risk of turbine failure. This paper proposes a novel micro-siting method designed for complex mountainous wind farms,which takes maximizing energy yield and ensuring turbine safety as the objective function. The proposed methodology takes power generation and safety performance of each turbine as the individual fitness. A case study on an actual operational wind farm reveals that the implementation of this method obtains a 1.6% increase in annual net power generation compared to conventional empirical approaches. Furthermore, the method ensures that safety identification indicators for each turbine remain beneath established high-risk thresholds, affirming the comprehensive safety status of the wind farm. The demonstrated results indicate that the method can serve as an instructive and practical tool for micro-siting optimization and risk mitigation in complex mountainous wind environments.