Abstract: Taking the coaxial two-body wave energy converter（WEC） as the research object and the wave field resources in Shandong Province as the background conditions, This paper first proposes the MATLAB-APDL-AQWA joint simulation system is proposed at first, through the secondary development of Python, the effect of PTO damping is considered to realize the full process simulation system to realize the full process simulation of wave energy-power, and compares the simulation results with the physical model test data in the literature. At the same time, the influence of floating body radius, mass parameters and PTO parameters on the average power of the device was investigated under random wave conditions. The research shows that the radius parameters and mass parameters of the twobody will significantly affect the average power of the device, and the energy gain of the device will first increase of the PTO damping coefficient, while the change of the PTO stiffness coefficient within a certain range has no obvious impact on the energy gain of the device.