Abstract: To analyze the effect of small changes in aerodynamic shape parameters on the aerodynamic and structural performance of wind turbine blades,a 5 MW offshore wind turbine blade was used as the research object,a CFD aerodynamic model of the blade and a finite element structural model of the composite material were constructed,considering the geometric constraints on the change of the surface shape of the blade element segment caused by the change of a certain airfoil parameter,the test level change of the chord length and twist angle of the blade element segment at different positions were calculated under the premise of satisfying the engineering constraints of the spreading smoothness,and an orthogonal test was designed under the interaction of aerodynamic shape parameters,the effects of aerodynamic shape parameters on aerodynamic torque and tip deflection of wind turbine blades were analyzed by using range analysis and variance analysis for three operating conditions with incoming wind speeds of 8.0,11.4 and 14.0 m/s. The results show that a 3% change in the test level of the aerodynamic shape parameters can affect about 6.7% of the aerodynamic performance change and about 15.0% of the structural performance change. The main effects of aerodynamic shape parameters are different in different position segments. The interaction between the parameters in different position segments has different degrees of influence on the blade aerodynamic torque and blade tip deflection.