Abstract: The necessity of configuring inertia regionally for large-scale renewable energy power system is analyzed. To achieve this goal,a suggestion is put forward,which says that the power synchronization control can be utilized to configure virtual inertia for voltage source converters. Based on these,a regional inertia configuration method considering a constraint on the rate of change of frequency（RoCoF）is proposed. In this method,firstly,the system to be studied is partitioned according to the consistency of frequency response.Then,the maximum unbalanced power of each region under disturbance is calculated by combining the internal disturbance in the region,the change of the power on transmission lines between different regions and the load response to the disturbed voltage. After that,the inertia demand could be obtained and the inertia configuration could be carried out regionally. Finally,in the case study of East China Power Grid,the inertia requirement of each region in the system is illustrated,and the effectiveness of the proposed regional inertia configuration method is verified.