Abstract: In this research,selecting a five-star hotel in Shanghai as a case study,a synergetic operation optimization model for combining the cooling,heating,and power system with solar energy was formulated. It aims to realize the minimization of operation and maintenance cost,with the constraints of the balance between energy supply and demand,equipment’s capacity and water quota. The obtained results presented as the operational strategy under various water quota demonstrated that,the water quota exerted the influence on total cost of entire system and power output of equipment. The water-consumption reduction and water-resource protection are realized at the expense of system economy.