Abstract: The three-dimensional N-S equation and SST k-ω model were employed to carry out CFD research on the NERL Phase VI rotating blade. Different rough zones were set on different spanwise and chordwise surfaces of the blade,then the effect of rough zone distribution on aerodynamic performance of the blade were investigated. The results show that the rough zones reduce the pressure difference between pressure side and suction side of the blade,which reduces the aerodynamic performance of the wind turbine. As the rough zone covers the whole blade surface,the negative pressure coefficient is reduced in the inner part of the blade and increased in the outer part of the blade. As the rough zone is set on the leading edge of the blade,a low pressure vortex is created on the suction side.With the increase of roughness,the strength of the vortex becomes higher,and the vortex location is closer to the leading edge. These effects are more obvious with the increase of roughness.