Abstract: In this study,lignin from eucalyptus was extracted with ionic liquid,and Lignin was phenol modified by cresol as phenolic agent with concentrated sulfuric acid as catalyst,then with NaOH as catalyst,lignin-based epoxy resin was synthesized via the epoxidation reaction between the phenol lignin and epoxy chloropropane. The result shows that the lignin extraction rate are 93.73% and the purity of regenerated lignin was 96.3% under the optimum conditions which areChClGlyionic liquid as the extractant,treatment temperature of 90 ℃,reaction time of 12 h and liquid-solid ration of 20∶1（g/g）. The optimal conditions for the synthesis of lignin-based epoxy resin were determined as follows:mass ratio of phenol lignin to epoxy chloropropane was 1∶2.5（g/g）,20% NaOH with the reaction temperature was 95 ℃ and the reaction time was 3 h. The maximum epoxy value of lignin-based epoxy resin reached0.364 under these optimized conditions.