Abstract: China has a large number of heavy-duty trucks,and the workload of drivers is extremely high. The space inside the cab is limited and enclosed. Improving the thermal comfort of drivers is of great significance for alleviating their fatigue and improving driving safety. In order to improve the thermal comfort of drivers while reducing energy consumption of heavy-duty trucks,this paper developed a heavy-duty truck cab energy supply system based on flexible PV modules. A physical model of the heavy-duty truck cab is built using the bestselling model among domestic heavy-duty trucks as an example. The application method of using flexible PV modules for power supply and semiconductor refrigeration devices to achieve local temperature control in the cab and integration of charging and discharging technology is explored,and the rationality of the energy supply system design is verified through experiments from two aspects:local temperature control strategy,PV power generation and variable load charging relationship. The research results show that,taking the Changsha region as an example,according to calculations,the total cooling load in summer inside the cab of a heavy-duty truck（during soomth operation） is 3995 W. Using six sets（eighteen pieces in total） of semiconductor refrigeration chip group can achieve local cooling effects in the cab. Using an artificial environment chamber to simulate the summer and winter environmental temperatures in the Changsha region for local temperature control effect experiments,the cooling and heating effects of this energy supply system can meet the thermal comfort needs of the human body,verifying the feasibility of the proposed local temperature control strategy. According to the PV power generation and variable load charging experiments,the annual power generation capacity of one XZL-A100 mono-Si flexible PV module is about 13.3 kWh. The PV power generation module of this energy supply system adopts six mono-Si flexible PV modules in parallel,and the power generation capacity can meet the electricity demand for local temperature control in the cab of heavy-duty trucks.