Abstract: The Cambrian Qiongzhusi Formation is one of the earliest series of strata for shale gas exploration and research in China. In the early stage, due to unclear understandings of the overall geological cognition and limited technological conditions, a number of wells were only deployed in the Weiyuan anticline and Changning anticline with a burial depth less than 3 500 m and a relatively gentle structure. The production rate of the wells is low, indicating a failure in the large-scale commercial development. Recently, major exploration breakthroughs have been made in Well Zi201 and Well Weiye1H, marking significant progress in geological cognition of the deep shale gas in Qiongzhusi Formation of the Deyang-Anyue aulacogen. The sedimentary environment of Qiongzhusi Formation is controlled by the aulacogen. The deep-water siliceous argillaceous shelf facies in the trough and deep-water silty argillaceous shelf facies on the slope of the trough edge are the dominant sedimentary facies zones, which are conducive to the enrichment and accumulation of shale gas. Vertically, Qiongzhusi Formation has developed multiple sets of shale reservoirs, mainly consisting of the 1st, 3rd, 5th, and 7th substrata. In particular, the 5th substratum is a key breakthrough layer with the total organic carbon content of 2.7% to 3.1%, porosity of 4.2% to 4.9%, brittle mineral content of 69.5% to 76.5%, gas content of 7.8 m³/t to 9.5 m³/t, and moderate maturity of 3.0% to 3.5%. The 3rd substratum is a potential exploration stratum. Qiongzhusi Formation is expected to realize multi-interval three-dimensional development. The bottom margin of the Cambrian System has a simple structure in the middle section of the aulacogen, lacking of obvious major faults. The pressure coefficient of Qiongzhusi Formation is generally above 1.8, and the preservation conditions are favorable. The aulacogen provides sufficient sedimentary space and material basis, as a result of which the shale in Qiongzhusi Formation is rich in hydrocarbon sources and has achieved a high volume of gas production; the existence of Leshan-Longnüsi paleo-uplift prevents the shale in Qiongzhusi Formation from excessive thermal evolution. A "aulacogen-paleouplift" shale gas enrichment model has been established, and it has been determined that the favorable exploration area of Qiongzhusi Formation is 4 400 km² and the resources amounts to 2×10¹²m³. The exploration breakthrough of shale gas in Qiongzhusi Formation has opened up another new field for achieving a trillion of cubic meters of reserves and a billion of cubic meters of production. Next, the geological-engineering integrated high-yield model of Well Zi201 will be promoted and applied to the exploration and development fields of marine deep and ultra-deep shale gas in the entire Upper Yangtze area of southern China.