Abstract: Based on the geochemistry data, well logging and sedimentary facies in Bozhong sag, an analysis was performed on high-quality lacustrine source rocks. In combination with regional seismic interpretation, this paper describes the distribution of high-quality source rocks in Bozhong sag, and then discusses the differences of source rocks under the effect of climate and tectonics. The results show that the high-quality source rocks formed in the saline environment controlled by climate and the rapid subsidence environment controlled by tectonics present different enrichment characteristics. The distribution area of high-quality source rocks in the Member 1 of Shahejie Formation under the main control of the salinized environment accounts for 81.9% of the depression area, showing a broad distribution; in Member 3 of Shahejie Formation and Member 3 of Dongying Formation under the control of tectonic subsidence, a significant positive correlation exists between the depression subsidence rate and the distribution area of high-quality source rocks in the depression. The redox interface of the lake controls the enrichment of high-quality source rocks in the longitudinal direction. Under the control of saline environment and rapid tectonic subsidence formed by climate, the development conditions of high-quality source rocks in Bozhong sag and adjacent areas can be divided into three categories dominated by salinized water, tectonic subsidence, and jointly by salinized water and tectonic subsidence, respectively. In the case of humid climate and low sedimentation rate, high-quality source rocks are not developed.