Abstract: The essential oil and gas pool-forming conditions of the uplift in the northern margin of Qaidam Basin including source rocks,assemblages of reservoirs and cap rocks,tectonic characters and its evolution,and types of pool-forming were analyzed. Oil and gas accumulated on Mahai-Dahonggou paleo-uplift mainly come from the adjacent Jurassic hydrocarbon-generation depression. The pool is characterized by more sources,thick layers,a long distance of oil-gas migration,abundant traps and large scale pools. The analysis on the main pool-forming controlling factors of the area shows that three paleo-uplifts will be the potential exploration targets in the northern margin of Qaidam Basin.