Abstract: The automatic calibration system of digital multifunctional standard device is developed to resolve such issues as numbers of calibration items to be adjusted by the digital multi-meter（DMM） for uncertainty caused by heavy workload of manual evaluation and error problems. The system can operate automatic measurement of the intrinsic errors, output stability and measurement repeatability. On the basis of the above,the automatic evaluation function of measurement uncertainty is also added. 34410A DMM is used to verify the automatic evaluation function of measurement uncertainty of the system. The results show that the system can effectively evaluate the measurement uncertainty of DMM. It is easy to operate and features with high accuracy. Manual errors can thus be avoided,and work efficiency will be improved as well.