Abstract: In order to further improve the power supply reliability of important loads, an optimization and resilience enhancement method of core backbone network framework under extreme weather was proposed. Firstly, the resilience of power system under extreme meteorological disasters was evaluated. The core backbone network framework under normal operation was established by the ant colony algorithm. And the core backbone network framework under outage situation was optimized by introducing the recovery index. Lastly, the relevant examples were analyzed, and the lifting method of system resilience was deeply analyzed. The results show that the proposed optimization method of the core backbone network framework can be adopted to optimize the restoration power supply path of important loads and generator units. The restoration efficiency and success rate are improved by simplifying the restoration process. The restoration time based on this method only takes 105 minutes, and the restoration success rate of this method is about 15% higher than that of other schemes. The research results have reference significance for the research of power grid construction.