The directional frictional anisotropy of snake-skin-inspired interfaces has great potential to improve the load-bearing performance of offshore uplift pile foundations and other engineering applications. Such interfaces are designed to withstand cyclic loads

including those induced by waves and earthquakes. To investigate the characteristics of directional frictional anisotropy of soil-structure bio-inspired interfaces under cyclic loading

a series of cyclic direct shear tests were conducted using an advanced interface cyclic shear apparatus. The study examined the effects of initial cyclic position

normal stress

bio-inspired interface morphology

and sand density on cyclic shear anisotropy

along with an initial exploration of shear strength characteristics following cyclic loading. The findings revealed that increasing initial position of the cycle and normal stress enhanced shear anisotropy under the cranial-caudal cyclic loading path

while reducing shear anisotropy under the caudal-cranial cyclic loading path. For interfaces at moderate densities

variations in the ratio of interface scale length to height exhibited negligible effects on shear anisotropy. However

as sand density increased

the influence of this ratio on shear anisotropy became more pronounced under the cranial-caudal cyclic shear path

with a slightly increased effect observed under the caudal-cranial cyclic path. Under constant stress conditions

the peak shear strengths in monotonic shear tests of the bio-inspired interfaces following both types of cyclic shear paths exceeded those observed without prior cyclic shearing

and it was also found that the peak interface friction angle increased significantly. These findings provide valuable insights for the optimization and practical application of bio-inspired interfaces in engineering projects.