The lithium(Li) resources were come from the granite pegmatite deposit and brine. This study were from macroscopic and microscopic to discuss the influence factors of Li enrichment of salt lake in Qinghai-Tibet Plateau. The lithium-rich salt lakes not only dominated by tectonic landform in high mountain-deep basin and the climate primary dry but periodism changed from drying to wet
but also dominated by others elements in lithium-rich salt lake. Low concentration of Mg and Ca
and the pH was strong basicity were more beneficial to the Li enrich in salt lake.