Progress on Bone Graft PEEK about Surface Modification

Xiao Tian-hua; Liu Rong-tao; Pang Yin-yu; Li Da; Liu Jia; Min Yong-gang

doi:10.12052/gdutxb.200118

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Progress on Bone Graft PEEK about Surface Modification

更新时间：2026-05-27

- Progress on Bone Graft PEEK about Surface Modification
- Vol. 38, Issue 2, Pages: 73-82(2021)
- 作者机构：
  
  1. 广东工业大学材料与能源学院,广东,广州,510006
  2. 东莞华南设计创新院,广东,东莞,523808
- 作者简介：
- 基金信息：
- DOI：10.12052/gdutxb.200118
  CLC： R318.08
- Online First：10 March 2021，
  
  Published：2021
- 稿件说明：
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肖天华, 刘荣涛, 庞贻宇, 李达, 刘佳, 闵永刚. 骨植入聚醚醚酮材料表面改性的研究进展[J]. 广东工业大学学报, 2021, 38(2): 73-82.

Xiao Tian-hua, Liu Rong-tao, Pang Yin-yu, et al. Progress on Bone Graft PEEK about Surface Modification[J]. 2021, 38(2): 73-82.
肖天华, 刘荣涛, 庞贻宇, 李达, 刘佳, 闵永刚. 骨植入聚醚醚酮材料表面改性的研究进展[J]. 广东工业大学学报, 2021, 38(2): 73-82. DOI： 10.12052/gdutxb.200118.

Xiao Tian-hua, Liu Rong-tao, Pang Yin-yu, et al. Progress on Bone Graft PEEK about Surface Modification[J]. 2021, 38(2): 73-82. DOI： 10.12052/gdutxb.200118.

摘要

聚醚醚酮(Polyetheretherketone

PEEK)是一种半结晶的合成聚合物

与传统修复骨缺损的生物材料相比

PEEK具有良好的生物相容性、化学稳定性、透光性和弹性模量与正常人骨相似等优点

已被广泛应用于骨科移植。但PEEK的生物惰性使其在临床应用中存在局限性

目前通过表面改性赋予PEEK材料表面生物活性是解决这个问题的有效途径。本文综述了近年来PEEK表面改性方法的研究现状和发展方向

其中着重介绍了物理改性、化学改性以及涂层改性

并分析了不同改性技术对于提高生物相容性的作用

最后指出PEEK表面改性骨移植材料在医学领域中继续发展需要解决的问题

要充分研究其在体内的每一阶段身体所做出的反应

并保证其表面处理在整个生命周期内不会退化或磨损正常组织。

Abstract

Polyetheretherketone (PEEK) is a class of semi-crystalline polymer. Compared with traditional bone repair materials

PEEK possesses good biocompatibility

chemical stability

light transmittance and elastic modulus which is similar to that of normal human bone. Therefore it has been widely used in transplantation. However

the biological inertia of PEEK limits its clinical application. At now

the surface modification is an effective way to solve this problem. The current status of research and direction of development about PEEK surface modification methods in recent years are reviewed. And physical modification

chemical modification and coating modification are emphasized. The effects of different modification technologies on improving biocompatibility were analyzed. Finally

the problems are pointed out that need to be solved for PEEK surface modified bone graft material to continue to develop in the medical field. The body's reaction must be studied fully at every stage after the bone graft material was implanted in the body. And it is ensured that the surface treatment does not degrade or wear away normal tissues throughout the whole life cycle.

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Keywords

references

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