Antibacterial Activity of Novel Quinoline Derivatives Containing Piperazine

WU  Li-Huan; DENG  Qi; ZHOU  Qiu-Gu

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Antibacterial Activity of Novel Quinoline Derivatives Containing Piperazine

更新时间：2026-05-27

- Antibacterial Activity of Novel Quinoline Derivatives Containing Piperazine
- Vol. 27, Issue 2, Pages: 40-42(2010)
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- Online First：25 June 2010，
  
  Published：2010
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吴利欢, 邓琪, 周秋谷. 新型含哌嗪基的喹啉衍生物的抑茵活性研究[J]. 广东工业大学学报, 2010, 27(2): 40-42.

WU Li-Huan, DENG Qi, ZHOU Qiu-Gu. Antibacterial Activity of Novel Quinoline Derivatives Containing Piperazine[J]. 2010, 27(2): 40-42.
吴利欢, 邓琪, 周秋谷. 新型含哌嗪基的喹啉衍生物的抑茵活性研究[J]. 广东工业大学学报, 2010, 27(2): 40-42. DOI：

WU Li-Huan, DENG Qi, ZHOU Qiu-Gu. Antibacterial Activity of Novel Quinoline Derivatives Containing Piperazine[J]. 2010, 27(2): 40-42. DOI：

摘要

为了寻找高效抑菌活性的新型药物，考察了13种含哌嗪基的喹啉衍生物对大肠杆菌、枯草杆菌、金黄色葡萄球菌的体外抗菌活性．结果表明：化合物3i、3j对大肠杆菌、枯草杆菌、金黄色葡萄球菌均有良好的抗菌效果，最低抑菌质量浓度为0．07 mg／mL．

Abstract

To develop novel antibacterial medicinals with high activity，antibacterial tests of 1 3 novel quinoline derivatives containing piperazine were conducted．The experimental results show that the compounds 3i and 3j possess good antibacterial activity against Escherichia coli，Bacillus subtilis and Staphylococcus aureus，and their MICs ale 0.07 mg／mL．

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