Study on Synthesis and Oxygen Permeability of Copolymer Hydrogel Containing Silicone for Contact Lens

CAI Li-bin; LIU Zheng-tang; CUI Ying-de; LI Shao-qiu; ZHANG Xiao-hong

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Study on Synthesis and Oxygen Permeability of Copolymer Hydrogel Containing Silicone for Contact Lens

更新时间：2026-05-27

- Study on Synthesis and Oxygen Permeability of Copolymer Hydrogel Containing Silicone for Contact Lens
- Vol. 22, Issue 3, Pages: 7-10(2005)
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- Online First：02 July 2005，
  
  Published：2005
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蔡立彬, 刘正堂, 崔英德, 黎少秋, 张小红. 含有机硅共聚物水凝胶合成及其透氧性能研究[J]. 广东工业大学学报, 2005, 22(3): 7-10.

CAI Li-bin, LIU Zheng-tang, CUI Ying-de, et al. Study on Synthesis and Oxygen Permeability of Copolymer Hydrogel Containing Silicone for Contact Lens[J]. 2005, 22(3): 7-10.
蔡立彬, 刘正堂, 崔英德, 黎少秋, 张小红. 含有机硅共聚物水凝胶合成及其透氧性能研究[J]. 广东工业大学学报, 2005, 22(3): 7-10. DOI：

CAI Li-bin, LIU Zheng-tang, CUI Ying-de, et al. Study on Synthesis and Oxygen Permeability of Copolymer Hydrogel Containing Silicone for Contact Lens[J]. 2005, 22(3): 7-10. DOI：

摘要

采用本体聚合法

以HEMA和NVP为单体

以Bis作为交联剂

用AIBN作为引发剂

加入有机硅(KH570)合成高透氧性的PVP共聚水凝胶接触透镜材料

研究了单体配比和温度等各因素与PVP共聚水凝胶接触透镜材料的透氧性能的关系.实验表明

共聚物水凝胶角膜接触镜材料的Dk/L值

随NVP的含量增加而增大;随KH570的增加而减小

当KH570用量为8%时

透氧率达到最大值45cm3/(cm2.s.mmHg);随渗透温度升高而增大;随膜厚度增大而减小.

Abstract

In this paper

by noumenon polymerization method

PVP copolymer hydrogel is made using(HEMA) and NVP as monomers

N′-methylene bisacrylamide(Bis) as crosslinker and azobis iso butyro nitrile(AIBN)as initiator.The oxygen transmissibility of PVP copolymer hydrogel is analysized.It is found that oxygen transmissibility increases with the increase of NVP in the copolymer hydrogel

and decreases with the increase of KH570 in the copolymer hydrogel.Dk/L amounts to the maximum 45cm~3/(cm~2·s·mmHg)when the content of KH570 is 8%;it increases with the increase of temperature

and decreases with the increase of the membrane’s thickness.

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Keywords

references

郑荣领,周电根,郑一仁. 角膜接触镜材料研究进展[J]. 国外医学.眼科学分册. 1999(04)

覃百花,邹翰. 软性角膜接触美容镜片的临床应用[J]. 眼科研究. 1997(04)

黎新明. 共聚物水凝胶接触镜材料的制备与性能研究[D]. 西北工业大学 2003

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