A non-thermal oxygen plasma（O

2

+

and O

3

） was produced by ionization and dissociation oxygen by a strong ionization discharge

and it was injected into a reaction tower of wastewater treatment for the degradation of recalcitrant organic pollutants in the wastewater. Four key plasma reactions took place in the reaction tower. Firstly

O

2

+

among non-thermal oxygen plasma reacted with H

2

O molecule to form trace hydroxyl radicals（·OH）. Secondly

an initiator（HO

2

·） with high reaction rate constant was generated by O

3

reacting with trace ·OH. And th

en

high concentration of ·OH with strong oxidizability and high reaction rate were formed by high concentration of O

3

under the action of HO

2

·. So the ·OH degraded recalcitrant organic pollutants into harmless small organic molecules non-selectively and rapidly. Finally ·OH mineralizes the small organic molecules into CO

2

and H

2

O. The experimental results show that the degraded concentration by non-thermal oxygen plasma will decrease from 145.0 mg/L to 25.5 mg/L within just 25 minutes

and the removal rate will reach 83.5%. Compared with conventional sewage treatment method

the method of degradation recalcitrant organic pollutants in the wastewater with non-thermal oxygen plasma formed by a strong ionization discharge has lower operating costs and initial investment

and the sewage treatment system is more simple. The advantages will provide an economic and practical new method for a deep-polluted wastewater reuse.