The minimum intensity（threshold） for activating action potential by pulse electrical stimulation is related to stimulus parameters. However

researchers mainly focus on duration-threshold relationships. The effects of frequency

one of the important pulse parameters

on the intensity threshold of action potential are rarely available in the literature. Consequently

on the basis of the HH model and cable model

we constructed a neuron action potential transmission simulation model. By analyzing action potential activation under different impulse stimulus

we investigated the influences of pulse width and frequency on threshold of action potential activation. Results show that the action potential can be induced by the supraliminal stimulation

and action potential can conduct along the axial direction. Time delay for each axial position is different. The subthreshold stimulation can not activate the action potential. Transmembrane potential will fluctuate along the axial direction as a result of external stimulus

and the farther away from the stimulation point

the smaller the fluctuation. With a wide pulse width（>3 ms） and low frequency（<100 Hz）

the threshold of action potential activation hardly change with the stimulus parameters. When the pulse width decreases（<3 ms）

the wider the pulse width

the lower the threshold. The threshold decreases linearly with the increase of pulse width in log-log scale. When the frequency increases（>300 Hz）

the effects of frequency on intensity threshold is similar to that of pulse width and the threshold decreases significantly with the increase of frequency

which is also linearly correlated in log-log scale. This study may provide theoretical references for the design of pulse generator in electrical stimulation therapy and the selection of stimulus parameters in neural regulation.