Abstract: With the large-scale growth and grid connection of the large-scale renewable energy such as wind power and photovoltaic, the problem of renewable energy abandonment rate and system reserve flexibility has become increasingly prominent. In order to solve the problem of the consumption of high proportion of the renewable energy and the flexible and stable operation of the energy system, a low-carbon and flexible dispatch of a high-proportion wind-photovoltaic multi-energy system with the comprehensive utilization of the large-scale hydrogen energy is proposed. The hydrogen energy comprehensive utilization unit composed of the electric hydrogen production, the hydrogen fuel cell, and the methane reactor is analyzed and modeled, and the scheduling strategy for the unit to participate in the operation of the multi-energy system is studied. The reserve capacity of the equipment in the unit is analyzed. Based on the operation characteristics of the equipment, the strategy of the hydrogen energy utilization unit thermal power joint reserve is proposed, thus the reserve optimization model is established. Finally, the comparative simulation analysis is carried out in the multi-energy system composed of the improved IEEE39-bus distribution network, the 20-bus gas network and the 6-bus heat network to verify the ability of the proposed scheduling method to promote the high proportion wind and photovoltaic consumption and provide the flexible reserve.