Abstract: Digitalization and intellectualization are the main characteristics of a new type of power system and an important development direction for operation and maintenance of traditional substation. To achieve intelligent perception and autonomous decision-making of substation equipment, it is important to establish a highly reliable wireless transmission network with large bandwidth in promoting the digitalization of substation operation and maintenance. This paper analyzes the advantages of WAPI wireless network for data transmission of substation equipment, and elaborates on a wireless data transmission scheme for substation equipment based on WAPI network. Based on the equipment in 220 kV Guoxiang substation, six intelligent operation and maintenance scenarios of the substation were demonstrated, including online monitoring of equipment, environmental monitoring, substation intelligent patrol, equipment interaction, operation assistance, and safety control. The optimization of working processes and improvement of safety management were achieved, which provides successful experience for digitalization and construction of the substations.