Abstract: With the increase of the wind power penetration, power systems will face the problems of insufficient inertia support and frequency response capability. Wind turbines can have frequency regulation capabilities through virtual inertia control and overspeed load reduction control. In this paper, based on the traditional unit commitment model, the frequency dynamic constraints are added, which take into account the frequency regulation of wind turbines. First, the time constant of virtual inertia for wind turbines with different load shedding is deduced. Then, the multi-machine system with the frequency regulation of the wind turbine is modeled, and the expression of the lowest value of the frequency after the disturbance is derived. Moreover, a unit commitment optimization model considering dynamic frequency constraints is constructed, and the multivariate piecewise linearization technology is used to solve the problem of highly non-linear characteristics of frequency constraints. Finally, a 10-generator system with wind power grid connection is taken as an example to carry out calculation and analysis. The results verify the feasibility of wind turbines participating in frequency regulation in the decision-making of unit commitment. Compared with the traditional unit commitment, the proposed model not only meets the economy, but also improves the system stability.