Abstract: Aiming at the problem of bus voltage control in DC microgrid, a dynamic compensation control strategy based on robust disturbance observer is designed to complete voltage compensation of DC-DC converter. Firstly, based on the architecture of DC microgrid, the theoretical analysis of the bus voltage fluctuation is carried out. Secondly, the state space mathematical model of the DC-DC converter of the DC microgrid system is established, and the input and output relationship of the control system is obtained. According to the robust dual-mass decomposition and the theory of Youla’s parameterized stability controller, the control architecture based on robust disturbance observer is obtained. The model matching theory is applied to compensate the output value generated by the current disturbance. The voltage loop compensation controller is solved by the linear matrix inequality（LMI）method. The current loop compensation controller is designed according to the dynamic structure diagram of the DC-DC converter.The results of semi-physical experiments show that the architecture can improve the dynamic performance of DC-DC converter without changing the structural parameters of the original system, and suppress DC bus voltage fluctuation caused by load switching, power fluctuation and AC side load imbalance, and enhances the robustness of the system.