Abstract: In order to solve the problems of the regional electricity spot market to coordinate the priority plan of trans-provincial sending and receiving power and the trans-provincial medium-and long-term trading system, and to make sure that the clearing results of the regional electircity spot market can truly reflect the pre-authorized trans-provincial transmission price and the network loss rate, a clearing model for the regional electricity spot market with the deviation correction of network losses in the transprovincial transmission grid is proposed. Firstly, taking the China southern regional electricity spot market as an example, the trans-provincial sending and receiving power trading entities and trading system are analyzed. Secondly, a deviation correction method of network losses considering both trading components and physical power flow is proposed, and based on this method, a clearing model for the regional electricity spot market with coupling of physical power flow and trading components is constructed. Finally, a 9-bus system and the China southern power grid simulation system are adopted to conduct simulation and verification. The simulation results show that the proposed deviation correction method and the clearing model for the regional electricity spot market can ensure that the trans-provincial transmission price and network loss rate can be reflected in the clearing price on the premise that the system safety operation constraints are satisfied. The priority plan of the trans-provincial sending and receiving power and the trans-provincial medium-and long-term trading system are effectively coordinated.