Abstract: Real information interaction is one of the key factors for coordinated and optimal dispatch of microgrid clusters. From a system of systems（SoS） perspective, the purpose of forming a microgrid cluster for the coordinated and optimal operation is to maximize the overall and individual benefits. Therefore, the information interaction that damages the efficiency of microgrid cluster operation is false information. False information injection is bound to have an impact on the safe, economic, and stable operation of microgrid clusters. In order to deal with the problem that false information injection affects the optimal operation of microgrid clusters, the SoS approach is introduced to build a fully distributed optimal dispatch model of microgrid clusters considering false information injection based on the architecture of microgrid clusters with false information injection, and a mechanism to detect,locate and punish false information in microgrid clusters is proposed by combining the improved alternating direction method of multipliers and consistency algorithm. This mechanism can effectively reduce the impact of false information injection on the coordinated and optimal operation of microgrid clusters. Finally, the effectiveness of the proposed model and the “false information” processing mechanism is verified through the analysis of cases.