Abstract: In the background of“carbon emission peak and carbon neutrality”, the next-generation distribution system will face the large-scale integration of new elements, such as distributed generators and electric vehicles in the future. In order to achieve the development goals of security, high-efficiency, environmental friendliness and intelligence, the distribution network may present the morphology of“honeycomb”, which is flexibly interconnected by multiple self-similar meshes. First, the advantages of the application of honeycomb topology in the distribution network are introduced. Three core features of honeycomb distribution network are clarified, which are regional autonomy and hierarchical clustering operation, multi-interface and modular design, and generalized flexibility of nodes and branches. Combined with the current situation and development trend of distribution networks,the construction foundation of core features is analyzed. Then, the key issues in the planning, operation and related interdisciplinary aspects of the honeycomb distribution network are summarized. Finally, the research ideas for the key issues are given combined with new methods and new indices. The work in this paper provides ideas and solutions for the systematic research and actual construction of the honeycomb distribution network.