Abstract: Virtual power plants exploit and utilize the flexibility of various types of distributed resources. It is an important measure to improve the safety of the power grid, reduce energy consumption costs for users, and reduce the curtailment of renewable energy. Under the environment of Energy Internet, virtual power plants are faced with technical challenges such as heterogeneous resources with multi-management body, strong uncertainty, and diversified power grid requirements in different regions. Based on the cloud-edge synergetic architecture, this paper designs a cloud-cluster-end hierarchical collaborative dispatch framework for multi-energy virtual power plants. This paper proposes some practical key technologies such as standardized modeling methods for the flexibility of heterogeneous distributed resources, online equivalent technology with day-ahead robust aggregation and intraday rolling modification method, and an interaction model for the virtual power plant and the upper power grid with diversified peak regulation requests considered. This paper designs and develops a dispatch module for park-level virtual power plants, which is applied in several engineering practical projects. The practicability of the proposed method and the universality of the modules are proven according to a case study for a real multi-energy park in Beijing of China.