Abstract: To achieve the optimize scheduling of multiple distributed energy systems within a virtual power plant,this paper proposes a comprehensive optimal dispatching strategy for multi-regional virtual power plants considering energy low carbonization. Firstly, a structure diagram of multi-regional within virtual power plant was constructed,which can achieve energy complementation between regions through the interaction among various integrated energy systems. Then, a power to gas（P2G） composite system was built, which consist of polymerize carbon capture power plant（CCPP）, P2G, fecal sewage treatment, cogeneration unit and gas boiler. It can help to enhance the renewable energy accommodation capacity and achieve the goal of maximizing operational efficiency. Aiming at the shortcomings of composite differential evolution algorithm, improvement measures are proposed to solve high-dimensional nonlinear objective function model. Finally, example analysis verifies that the method proposed in this paper can achieve the optimize scheduling of electricity and heat energy among multiple regions, enhance the renewable energy accommodation capacity, and improve the operational efficiency and carbon emissions of virtual power plant.