Abstract: In order to clarify the ground treatment method of sandy soil in Hotan desert area in northwest China, this paper selects a power project with sandy soil combination of typical aeolian and alluvial genesis in Hotan desert area as a case study and carries out a systematic research. The feasibility of the ground treatment methods is verified by determining the bearing capacity and deformation capacity of the foundation soil after treatment with the dynamic compaction method and vibrofotation stone column method, and the specific construction parameters,and construction techniques are determined to guide the formal construction of the foundation treatment. The research framework of this study can be directly extended to the design and construction of foundation treatment of other stratigraphic structures,and the research results of this paper also provide an empirical basis for power projects with similar stratigraphic conditions.