Abstract: Inspection robot is an important part of intelligent power plant, which can significantly improve the intelligent level of inspection operations. High-precision positioning is the key to ensuring the reliable and stable operation of the inspection robot. Start from the design idea of the patrol inspection system, define the system functions. Then, the design scheme of the patrol inspection system is given from the hardware architecture and software functions. Finally, the deployment of the patrol inspection task and the processing of the patrol inspection results are studied. The use of the autonomous system can greatly improve the efficiency of patrol inspection and provide a more powerful tool for grasping the actual operation of the power plant. The robot autonomous patrol inspection system products developed ensure the safe operation of equipment in key areas while achieving staff reduction and efficiency increase, help the construction of smart power plants.