Abstract: The design of 110 kV transmission lines is described based on practical engineering cases.By comparing the planning of route schemes as well as the technical and economic aspects of the conductors,configuring the grounding wire in the long term, and selecting tower and foundation models that are suitable for the project, the quality of the engineering design can be ensured better. By reasonably selecting the line route,lead grounding wire parameters, meteorological conditions, and thus typical iron tower modules in the design,the scheme shows more rational so as to obtain better engineering economic and technical indicators, and more in line with the construction requirements of "environmentally friendly and resource saving" proposed by State Grid Corporation of China for transmission and distribution projects.