Abstract: In view of the increasing demand for power failure of main network equipment due to the expansion of power grid scale year by year, the existing analysis of the impact of maintenance power failure on the system outside the fault area is not comprehensive, the amount of calculation is large when analyzing risks, and the technical level of relevant personnel is required to be high, a power grid security and stability system based on maintenance sensitivity and network reconfiguration is designed in this paper. Firstly, the method of obtaining power grid data model and the significance of model data inclusion are introduced; The risk analysis method of power grid operation in the mode of multi equipment simultaneous maintenance is analyzed, and the equipment maintenance sensitivity is sorted to find the equipment with the greatest risk of simultaneous maintenance; For the problems of power flow out of limit and loss increase that may occur during maintenance, network reconfiguration is adopted to eliminate out of limit and reduce loss.