Abstract: Liquid lead-bismuth eutectic（LBE） has a wide range of applications in new nuclear reactors and accelerator-driven subcritical systems（ADS） due to its good thermal conductivity and chemical inertness. However, its severe corrosion to structural materials at medium and high temperature limits its development. Studying the corrosion process and mechanism of liquid lead-bismuth eutectic is of great significance to the development of liquid lead-bismuth eutectic reactor. At present, the widely used corrosion analysis model simplifies the three-dimensional convection-diffusion equation to one-dimensional ordinary differential equation for analytical solution. Although the calculation efficiency is high, the accuracy is poor. Based on the CFD method and starting from the three-dimensional convection-mass transfer diffusion equation, this paper uses OpenFOAM open source software to establish a non-isothermal liquid metal closed loop corrosion model, and simulates the rate of corrosion and deposition on the wall of the loop. The results verify that the active oxygen control technology has a good effect and can significantly reduce the deposition rate of corrosion and corrosion products. In addition, a sensitivity analysis is performed on several important parameters, and the results show that the corrosion rate and deposition rate of the loop have a negative correlation with the pipe diameter and length, but have a positive correlation with the flow velocity.