Abstract: In this paper, load rate of 3917 sets of 10kV distribution transformers in regional power grid of Hubei Province during 2016 is statistically analyzed from four aspects, including the annual maximum load rate and the annual average load rate of single distribution transformer, as well as the mean of the daily maximum load rate and the mean of the daily average load rate of all distribution transformers. The loss of single distribution transformer and actual loss of all distribution transformers in regional power grid are studied. The conclusions can provide a reference for better understanding of actual operation of distribution transformer, and guiding operation and planning of distribution network.