Abstract: Typical temperature control loads, like Heating, ventilating and air conditioning(HVACs), distributed comprehensively which have large potential to respond to system control. A multi-layer simulation modeling methods of HVACs was proposed in this paper, including multi-agent system modeling method of HVACs and interfaces developing method. With these interfaces,the automatic dispatching system, D5000, can be driven by HVACs simulation system. At last, we simulated HVACs’ response process, by participating day-ahead market, and the results were analyzed.